NCT03881566已完成不适用
Study of Usefulness of Presepsin as Early Detective Marker of Sepsis in Immunodeficiency ICU Patients
Jongmin Lee1 个研究点 分布在 1 个国家目标入组 119 人开始时间: 2019年3月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 119
- 试验地点
- 1
- 主要终点
- Area Under the Receiver Operating Characteristic Curve (ROC-AUC) of the Plasma Presepsin Concentration for Discriminating Between immunocompetent and immunocompromised patients.
研究概览
简要总结
This is an observational study to evaluate the diagnostic and prognostic value of presepsin in the critically-ill immunocompromise patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or female aged ≥ 19 years
- •Appropriate clinical data to enable classification into sepsis
- •Written informed consent by the patient or legally authorized representative
- •Critical illness consistent with sepsis, to be enrolled within 24 hours of presentation
排除标准
- •No informed consent
- •A patient who is judged to be unable to make a voluntary decision by understanding information about this research due to cognitive vulnerability
结局指标
主要结局
Area Under the Receiver Operating Characteristic Curve (ROC-AUC) of the Plasma Presepsin Concentration for Discriminating Between immunocompetent and immunocompromised patients.
时间窗: up to 7 days
For the analysis, plasma presepsin levels on Day 0 will be used. Sepsis was made on Day 7 or day of discharge. ROC-AUC of presepsin for discriminating between immunocompromised and immunocompetent patients is compared to that of procalcitonin.
次要结局
- survival at ICU discharge or day 28 after enrollment(28 days)
研究者
Jongmin Lee
Professor
Seoul St. Mary's Hospital
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
Presepsin Biomarker for Ventilator-associated Pneumonia Diagnosis in COVID-19 PatientsVentilator Associated PneumoniaCovid19NCT04840940San Luigi Gonzaga Hospital50
招募中
不适用
Predictive Values of Presepsin Levels in ASciteS in Patients With Chronic Liver FailureAscites HepaticCirrhosis, LiverLiver FailureNCT06224023Carol Davila University of Medicine and Pharmacy30
终止
不适用
Interest of the Presepsin Assay as a Biomarker of Bacterial Infection, in the Management of Newborns and Infants Under 3 Months of Age Admitted for Fever in Pediatric Emergency Service (Presepsin)Newborn SepsisFeverNCT04076345University Hospital, Clermont-Ferrand31
尚未招募
不适用
Role of Presepsin as a Novel Biomarker in Diagnosis of Neonatal SepsisNeonatal SepsisNCT06633770Sohag University100
招募中
不适用
The Role of Presepsin and Other Markers in Early Diagnosis and Evaluation of Treatment of Pediatric Bacterial Infections.bacterial infectionJPRN-UMIN000012539Faculty of Medicine, Osaka Medical College100