Does Deficiency in Vitamin D Induced Hypercoagulation or Thrombin Generation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- the correlation between vitamin D levels and endogenous thrombin potential
研究概览
简要总结
Working hypothesis and aims: The aim of our study is to investigate whether vitamin D deficiency could cause increased thrombin generation and a hypercoagulable state healthy volunteers.
Methods:
In total 400 healthy volunteers are planned for inclusion in this trial. After signing an informed consent two blood samples will be obtained from each participant.
Expected results: invastigator expect to find that volunteers with vitamin D deficiency will have thrombin generation curve compatible with hypercoagulable state and returning to normal after treatment with vitamin D
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age >18 healthy naive to drug treatment -
排除标准
- •no exc criteria
研究组 & 干预措施
healthy voulnters
干预措施: Vitamin D (Drug)
结局指标
主要结局
the correlation between vitamin D levels and endogenous thrombin potential
时间窗: 3 month
one blood test
次要结局
未报告次要终点
研究者
Elias mazen
Director of Internal Medicine C
HaEmek Medical Center, Israel