Study of the Association Between Digital Osteoarthritis and Lower Limb Osteoarthritis (Knee and Hip) in Terms of Severity and Evolution - Khoala Group Ancillary Project / Cohort Khoala
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 479
- 试验地点
- 1
- 主要终点
- Kellgren and Lawrence score
研究概览
简要总结
Among the risk factors for lower limb osteoarthritis, if obesity is probably the most studied, digital osteoarthritis received increasing interest in recent years. Recent publications have highlighted a link between obesity and digital osteoarthritis, but also a very probable link between digital osteoarthritis and structural progression of knee osteoarthritis. Few data including hip exist and need to be confirmed on larger scale studies. We have with "Khoala" a national multiregional cohort of symptomatic gonarthrosis and coxarthrosis representative of the general population (which is rarely the case in the literature) including X ray, clinical and biological follow-up (hips and / or knees).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •men or women aged 40 to 75 years
- •with symptomatic osteoarthritis of the hip and / or knee (femoro-tibial), unilateral or bilateral
- •with a confirmed diagnosis (criteria of the American College of Rheumatology :ACR) and Kellgren and Lawrence radiological stage ≥ 2.
排除标准
- •painful hip or knee prosthesis
- •osteotomy in the past
结局指标
主要结局
Kellgren and Lawrence score
时间窗: Change at 2 years
Kellgren and Lawrence score for hip or knee
次要结局
- Harris score(Harris score at 2 years)
