Identification of Factors That Predict Early Haemodialysis Arteriovenous Fistula Failure
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 105
- 试验地点
- 1
- 主要终点
- Identification of the pre/perioperative factors that predict early AVF failure (eAVFF)
研究概览
简要总结
Arteriovenous fisutla (AVF) is the vascular access of choice for hemodialysis but has a high early failure (eAVFF) rate. eAVFF can be defined as thrombosis/stenosis and Doppler ultrasound (DUS)-based failure-to-mature parameters such as postoperative blood flow (PostQa) < 500 ml/min, AVF-vein diameter (PostVD) < 5 mm, and AVF-vein depth (PostVDepth) ≥ 6 mm. We explored whether common risk factors for eAVFF could predict these eAVFF parameters and venous distensibility: the latter is largely overlooked as a potential eAVFF parameter.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients (≥ 18 years)
- •Patients who had undergone distal (radioradial and radiocephalic) or proximal arteriovenous fistula (AVF) access creation surgery between 2016 and 2021 at the CHR Metz-Thionville.
- •Patients who underwent preoperative and postoperative Doppler ultrasound (DUS) ≤ 4 months after surgery.
- •Patients with central venous catheter (CVC) at surgery
排除标准
- •Patients using the fistula for intermittent plasmapheresis
- •Patients with a radiobasilic AVF or arteriovenous graft
结局指标
主要结局
Identification of the pre/perioperative factors that predict early AVF failure (eAVFF)
时间窗: up to 3 months after AVF creation
Comparison of preoperative and intraoperative results according to composite factors of arteriovenous fistula failure: Qa blood flow \< 500 ml/min, postoperative venous internal diameter PostVD \< 5 mm; complications: presence of stenosis, presence of thrombosis; AVF vein depth (external diameter) (PostVDepth) ≥ 6. The following variables were compared between groups: age (years) , sex (Man/Women), body mass index (kg/m2), Comorbidities \[Diabetes mellitus (yes/no), obesity (yes/no)\], Preoperative hemoglobin (g/dl); locoregional anesthesia (yes/no), Central Venous Catether (CVC) use (yes/no); CVC use on same side as AVF (yes/no); AVF on left side of body (yes/no); Distal AVF location (yes/no); Preop AVF vessel diameter (artery and vein; mm).
次要结局
- Identification of the pre/perioperative factors that predict the early postoperative AVF blood flow (PostQa)(up to 3 months after AVF creation)
- Identification of the pre/perioperative factors that predict the early postoperative venous internal diameter (PostVD)(up to 3 months after AVF creation)
- Identification of the pre/perioperative factors that predict the early postoperative AVF stenosis and/or thrombosis(up to 3 months after AVF creation)
- Identification of the pre/perioperative factors that predict the early postoperative skin to AVF distance(up to 3 months after AVF creation)