NCT07566975招募中不适用
Real-World Assessment of VEVYE® for Short-Term Symptom and Sign Improvement of Dry Eye Disease in a Neuro-Ophthalmology Clinic: A 6-Month Prospective Observational Study
Neuro-Ophthalmology of Texas1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2026年3月31日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Corneal fluorescein staining
研究概览
简要总结
patients from a Neuro Ophthalmology who have dry eye, some of which have neurotrophic keratitis are being analyzed after treatment with Vevye
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age18 yr or older Diagnosis of neuro-ophthalmic condition Clinical diagnosis of dry eye disease OSDI score of 23 or greater at baseline Objective sign present Indicated for VEVYE prior to enrollment Ability and willingness to complete study visits and questionnaires
排除标准
- •Patients with a corneal ulcer Use of another cyclosporine or lifitegrast product within 30 days of baseline Ocular surgery within 30 prior to baseline Active ocular infection or severe ocular surface condition unrelated to DED Contact lens wearers ( must be off contacts for 30 days and the duration of trial) Any condition that prevents compliance or informed consent Subjects with severe scarring / zero sensitivity
研究组 & 干预措施
Dry Eye without neurotrophic changes
干预措施: Cyclosporine ophthalmic solution 0.1% (Other)
Dry Eye with neurotrophic changes
干预措施: Cyclosporine ophthalmic solution 0.1% (Other)
结局指标
主要结局
Corneal fluorescein staining
时间窗: Baseline compared to week 4
pre vs post treatment
次要结局
未报告次要终点
研究者
研究点 (1)
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