Comparative evaluation of Platelet Rich Plasma (PRP) and Platelet Rich Fibrin (PRF) as pulpotomy agents in young permanent molars: A Spilt Mouth Radomized Controlled Trial
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Comparison of clinical success of PRP and PRF
研究概览
简要总结
This study is a randomized, split mouth design, single blind trail comparing the efficacy of Platelet Rich Plasma (PRP) and Platelet Rich Fibrin (PRF) as a pulpotomy agent in 25 children 7 to 10 year old with 50 young permanent molars present bilaterally in maxillary or mandibular arch. The study will be conducted in Terna Dental college, Navi mumbai, India. Pulpotomy procedure will be carried out in young permanent molars. The patient will be recalled after 3, 6 and 12 months for clinical and radiographical evaluation. The primary outcome measures will be efficacy of both the materials at 3 months follow up. The secondary outcomes will be efficacy of both the materials as pulpotomy agent at 6 month and 12 month follow up.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 7.00 Year(s) 至 10.00 Year(s)（—）
- 性别
- All
入选标准
- •Large carious or mechanical exposure (more than 1 mm) of the vital coronal pulp
- •Absence of symptoms indicative of advanced pulpal inflammation such as spontaneous pain or history of nocturnal pain
- •Absence of clinical signs or symptoms suggesting a nonvital tooth such as suppurating sinus, soft tissue swelling.
- •Restorable tooth structure.
- •No evidence of external and/or internal root resorption
- •No widening of periodontal ligament (PDL) space
- •Absence of furcal or periapical radiolucency
- •Absence of canal calcification or pulp stone.
排除标准
- •Uncontrolled bleeding during the amputation of coronal pulp tissue
- •Children with medical conditions or any associated systemic condition.
结局指标
主要结局
Comparison of clinical success of PRP and PRF
时间窗: 3 months
次要结局
- Comparison of clinical and radiographic success of PRP and PRF(6 months and 12 months)