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临床试验/NCT06663592
NCT06663592
已完成
不适用

Effectiveness of Slider and Tensioner Neurodynamic Mobilization Techniques in Patients With Cervical Radiculopathy: A Randomized Controlled Trial

Cairo University1 个研究点 分布在 1 个国家目标入组 36 人2024年11月15日

概览

阶段
不适用
干预措施
Conventional treatment
疾病 / 适应症
Cervical Radiculopathy
发起方
Cairo University
入组人数
36
试验地点
1
主要终点
Visual Analogue Scale
状态
已完成
最后更新
23天前

概览

简要总结

The goal of this randomized controlled trial is to investigate the effects of adding slider neural mobilization technique compared to tensioner neural mobilization technique to conventional physical therapy treatment on pain, function, cervical range of motion, hand grip strength, and electrophysiological parameters of the median nerve in patients with cervical radiculopathy.

详细描述

Cervical radiculopathy (CR) is a condition where the nerve root of a spinal nerve is compressed or impaired, causing the pain and symptoms to spread beyond the neck, radiating to the shoulder, and upper limb. Cervical radiculopathy primarily results from an impingement and inflammation of a nerve root induced by a space-occupying lesion that reduces the size of the intervertebral foramen, as a degenerative lesion of the zygapophyseal joint, or it is associated with a cervical disc derangement. Patients presenting with CR complain of neck, periscapular, and radicular pain into the hand and arm. As well as neurologic symptoms such as sensory disturbances (paresthesia or numbness), muscle weakness with reduced tendon reflexes in the affected nerve root, or a combination of these signs and symptoms. The reported annual incidence of CR is 85 cases per 100,000 people in the population, while the prevalence is 3.5/1000 persons. The C7 nerve root is most frequently impacted, with more than half of all cases affecting this level. Several studies utilized therapeutic exercises, manual therapy, other modalities, cervical collars, cervical traction, postural education, and different medications such as drugs and steroid injections in the conservative management for cervical radiculopathy in its different stages. The neural mobilization (NM) is a manual therapy method that improves neural flexibility, lowers dynamic sensitivity of the nervous system, increases blood flow, and relieves pain; for that, improved neural mobility and alleviated pain increase joint range of motion (ROM). The NM techniques are delivered by two techniques, "sliding/gliding" and "tensioning." Tensioner technique generate tension from both ends of the nerve, while sliders involve gliding of the nerve relative to its surrounding structures by performing joint movements that elongate the nerve bed with minimal strain. In addition, sliders are usually less aggressive than tensioners, and their use might be indicated at early disease stages. Both techniques aid in preventing the formation of adhesions, reducing endoneurial pressure, reducing intraneural edema, increasing nerve oxygenation, and decreasing ischemic pain. Studies that used sliders and tensioners techniques in their clinical studies showed significant changes in biomechanical factors such as patients' self-reports of pain, disability, ROM, endurance, and muscle strength in the management of musculoskeletal neck disorders with nerve-related symptoms. Therefore, what are the possible effects of adding the tensioner neural mobilization technique versus the slider neural mobilization technique to conventional physical treatment in treating patients with cervical radiculopathy?

注册库
clinicaltrials.gov
开始日期
2024年11月15日
结束日期
2025年4月15日
最后更新
23天前
研究类型
Interventional
研究设计
Parallel
性别
All

研究者

责任方
Principal Investigator
主要研究者

Hiba Mohammad Hasan

Principal Investigator

Cairo University

入排标准

入选标准

  • Current continuous or intermittent pain that has persisted for more than 3 months.
  • Motor, reflex, and/or sensory changes in the upper limb.
  • Both genders aged 30-50 years.
  • Three positive special tests out of five as a predefined diagnostic criterion from the following tests: Upper Limb Neural Tension A (ULNT) test for the median nerve, Spurling's test, compression test, cervical distraction test, less than 60° cervical rotation towards the symptomatic side, and Valsalva maneuver.
  • A motor nerve conduction study, F wave, and H reflex were performed in the involved limb to confirm CR.

排除标准

  • History of surgical procedures for cervical or upper extremity.
  • Clinical signs or symptoms of medical red flags (infection, cancer, and cardiac involvement).
  • Patients with neck pain for signs and symptoms of serious pathology, upper cervical ligamentous insufficiency, unexplained cranial nerve dysfunction, and spinal fractures.
  • Any systematic disease such as rheumatism and tuberculosis, cervical myelopathy, or multiple sclerosis.
  • Systemic disease is known to cause generalized peripheral neuropathy, such as diabetes mellitus.
  • Complete loss of sensation along the involved nerve root.
  • Upper limb compression syndrome, such as thoracic outlet syndrome, carpal tunnel syndrome, and pronator syndrome.
  • Pregnant woman.
  • Patients who have received any physical therapy of the cervical region in the past 3 months.

研究组 & 干预措施

Control group A (conventional treatment)

Conventional treatment, including hot pack, stretching of the neck muscles, cervical isometrics exercise.

干预措施: Conventional treatment

Experimental group B (Tensioning neural mobilization with addition to conventional treatment)

Median nerve neural tensioning mobilization with addition to conventional treatment

干预措施: Tensioner Neuro Dynamic Mobilization

Experimental group C (Sliding neural mobilization with addition to conventional treatment)

Median nerve sliding neural mobilization with addition to conventional treatment

干预措施: Slider Neuro Dynamic Mobilization

结局指标

主要结局

Visual Analogue Scale

时间窗: At baseline, to the end of treatment at 4 weeks.

to measure neck pain with score extended from 0 to 10, minimum score 0 (no pain), highest score 10 (worst pain).

The Arabic Version Of Neck Disability Index

时间窗: At baseline, to the end of treatment at 4 weeks.

to assess the level of disabilities in patients with neck pain, in % points.

Cervical Range of Motion

时间窗: At baseline, to the end of treatment at 4 weeks.

to measure the full cervical rotation using CROM device in degrees

Hand Grip Strength

时间窗: At baseline, to the end of treatment at 4 weeks.

to measure hand grip strength using hydraulic dynamometer, in kilogram.

Nerve Conduction Study

时间窗: At baseline, to the end of treatment at 4 weeks.

Motor conduction study for the median nerve, to measure conduction velocity (m/second), distal latency (ms), and amplitude(mV).

F wave

时间窗: At baseline, to the end of treatment at 4 weeks.

F wave for the median nerve to measure latency (ms).

H-Reflex

时间窗: At baseline, to the end of treatment at 4 weeks.

H-Reflex for the median nerve to measure latency (ms), amplitude (mV), H-R ratio (%).

研究点 (1)

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