The Value of Postoperative CRP Levels to Predict Postoperative Vaginal Cuff Hematoma
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 106
- 主要终点
- Relationship between CRP Levels and cuff hematoma; cuff hematoma measurement
研究概览
简要总结
After laparoscopic hysterectomy, authors aimed to determine cuff hematoma and a postoperative CRP value to help predict the other complications.
A total of 136 patients who underwent total laparoscopic hysterectomy (TLH) were evaluated. CRP, White blood cell (WBC) and hemoglobin values (Hb) were measured on the 1st, 2nd and 7th days before and after the operation. Complications, pre-postoperative vaginal length and female sexual function were evaluated. Fourteen patients who developed cuff hematoma during postoperative follow-up were analyzed with the receiver operating characteristics (ROC) curve. ROC curves with the largest area under the curve for each inflammatory marker were compared in order to define the marker with higher diagnostic accuracy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •women who underwent TLH operation with benign gynecological indications
排除标准
- •Decided to switch to laparotomy during operation
- •postoperative complication due to relaparotomy
- •infection (including urinary system and lung infections)
- •Blood transfusion after TLH
- •with rheumatic diseases
- •length of hospital stay due to wound infection
结局指标
主要结局
Relationship between CRP Levels and cuff hematoma; cuff hematoma measurement
时间窗: 15 days
The patients were called to the outpatient clinic after the hysterectomy and evaluated by transvaginal ultrasonography (tvusg) for cuff hematoma.hematoma dimensions recorded in centimeters.
Relationship between CRP Levels and cuff hematoma; crp levels
时间窗: 1 week
The value of Postoperative CRP Levels to predict Postoperative Vaginal Cuff Hematoma ; To evaluate tissue trauma and surgical inflammatory responses, venous peripheral blood samples (C-reactive protein) were taken on the first, second and seventh day postoperatively. CRP values were measured under standardized conditions using turbidometry. CRP levels (mg / dl) were recorded.
次要结局
未报告次要终点
研究者
Pınar Kadirogulları
Principal investigator
Kanuni Sultan Suleyman Training and Research Hospital