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临床试验/NCT01111760
NCT01111760已完成不适用

Radiation Dose From Computed Tomography Before and After Implementation of a High Pitch Dual Spiral Technique

Michael Gallagher1 个研究点 分布在 1 个国家目标入组 334 人开始时间: 2010年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
334
试验地点
1
主要终点
Comparison of the radiation dose for chest CT examinations using current technology with radiation dose exposure using the newest generation CT scanner.

研究概览

简要总结

The purpose of this study is to compare the radiation exposure of a variety of chest CT examinations performed on the current state of the art CT scanners (64 slice, dual source CT scanner) with the radiation exposure for identical chest CT examinations performed on the Siemens Flash CT scanner (high pitch dual source spiral technique).

详细描述

Computed tomography has emerged as the "gold standard" for the diagnosis of a broad range of medical diagnoses. For cardiac imaging alone, the installation of CT scanners in US cardiology practices alone has tripled over the past 2 years. Patients who undergo cardiac CTA (computed tomography angiography) may be subjected to relatively high doses of ionizing radiation (ie. 4 times annual background radiation) during the diagnosis and management of coronary artery disease. Current radiation doses for cardiac CT examinations are comparable to the effective doses for patients undergoing nuclear stress tests or cardiac catheterization (ie. approximately 10-15 milliSieverts). In addition, non cardiac CT protocols, such as chest CT examinations for the evaluation of pulmonary arteries, thoracic and abdominal aorta, and lung nodules, are associated with significant radiation exposure. Many patients undergo repeated CT examinations over several years for such pathology. There is a growing public concern regarding the cancer risk associated with such radiation.

Recent major technological advances have been made with the advent of newer generation CT scanners which allow significant radiation dose reduction. One such scanner, the dual source CT, is a new high pitch dual source spiral technique that offers the ability to image a patient's chest with ECG gated imaging protocols within a single second. These technological advances allow significant radiation dose savings, often resulting in effective radiation doses of less than one millisievert (mSv).

研究设计

研究类型
Observational
观察模型
Case Only

入排标准

性别
All
接受健康志愿者

入选标准

  • All patients who undergo chest CT examinations (including cardiac CTA, and non cardiac CT examinations including pulmonary embolism, lung nodule and aortic pathology protocols)

排除标准

  • 未提供

结局指标

主要结局

Comparison of the radiation dose for chest CT examinations using current technology with radiation dose exposure using the newest generation CT scanner.

时间窗: Time of CT scan

The primary objective of this study is to compare the estimated radiation dose for chest CT examinations (cardiac and non cardiac) performed using current technology (ie. Retrospective gated CT examinations on the 64 slice and dual source Definition Siemens CT scanners) with the radiation exposure using the newest generation CT scanner (high pitch dual source spiral technique).

次要结局

未报告次要终点

研究者

发起方
Michael Gallagher
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Michael Gallagher

Cardiologist

William Beaumont Hospitals

研究点 (1)

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