Randomised controlled double blind study to compare the efficacy of two doses of magnesium sulphate as an adjuvant to local anesthetics in supraclavicular block
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- DURATION OF POST OPERATIVE ANALGESIA
研究概览
简要总结
This is a randomised controlled double blinded prospective study to compare the efficacy of two different doses of magnesium sulphate 150 mg and 250 mg when added to local anesthetics in USG Guided supraclavicular block in elective upper limb surgeries .Total 90 patients aged between 18 to 60 years will be divided into two groups , Group M1- 12 ml 0.5% Bupivacaine plus 12 ml 2% lignocaine with adrenaline plus magnesium sulphate 150 mg( 0.3ml), Group M2- 12 ML 0.5% Bupivacaine plus 12 ml 2% lignocaine with adrenaline plus magnesium sulphate 250 mg(0.5 ml) and we compare the following parameters- Onset and duration of sensory block, Onset and duration of motor block, Duration of post operative analgesia, total analgesic requirement in 24 hours & monitor for side effects if any.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •PATIENT AGED BETWEEN 18 TO 60 YEARTS OF AGE BOTH SEXES ASA GRADE I AND II POSTED FOR ELECTIVE UPPER LIMB SURGERY UNDER SUPRACLAVICULAR BLOCK.
排除标准
- •PATIENT REFUSAL TO PARTICIPATE IN STUDY PATIENT ALLERGIC TO LOCAL ANAESTHETIC AGENTS PATIENT ON CHRONIC TREATMENT WITH CALCIUM CHANNEL BLOCKERS PATIENT WITH HEART BLOCK PATIENT ON ANTICOAGULANTS PATIENT WITH PRE EXISTING NEUROPATHY.
结局指标
主要结局
DURATION OF POST OPERATIVE ANALGESIA
时间窗: ONSET AND DURATION OF MOTOR AND SENSORY BLOCK
次要结局
- TOTAL ANALGESIC REQUIREMENT(POST OPERATIVELY FOR TWENTY FOUR HOURS)