Evaluation of the Efficacy of Injectable Platelet-rich Plasma in Orthodontic Tooth Movement Acceleration With Clear Aligner Therapy
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 10
- 主要终点
- Measuring the amount of tooth movement in group of clear aligner therapy and group of clear aligners with injectable platelet-rich plasma by little's irregularity index
研究概览
简要总结
Aim of the study is evaluation of the efficacy of injectable platelet-rich plasma in orthodontic tooth movement acceleration with clear aligner
详细描述
Malocclusion is frequently viewed as detrimental to one' self-worth and overall physical, social, and mental health. On the past few years, more and more grown-up patients have persued orthodontic care and they want attractive and pleasant options instead of traditional braces. CLEAR aligners that meet this need are also subject to technological advancements in the materials used and the methods of production. Consequently, CAT has merged as the leading trend in orthodontic innovation. The primary advateges of clear aligner therapy include the option to remove while eating, enhanced oral hygiene practices, less discomfort for patients,and the capability to visualize the treatment outcome through computer applications.
Clear aligners need to be removed during eating, when drinking hot beverages that may lead to warping, while having sugary beverages, and also when cleaning teeth.
Today, numerous methods have emerged to accelerate orthodontic tooth movement, encompassing invasive,minimally invasive,and non-invasive strategies.
IN addition, the use of medications and autologous biological solutions, like platelet-rich plasma, has been suggested.
One of the recently utilized local agents to accelerate the process of orthodontic tooth movement is platelet-rich plasma.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 15 Years 至 25 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Non-extraction cases
- •Complete permanent dentition
- •Good oral hygiene
- •Healthy periodontal condition
- •Single or double arch treatment
- •No therapeutic intervention planned intermaxillary or other intraoral or extraoral appliances including lip bumper, elastics and maxillary expansion appliances
- •mild to moderate crowding
排除标准
- •Systemic medical conditions
- •Dental anomalies in tooth size or shape
- •Current use of anti-inflammatory medications
研究组 & 干预措施
Clear aligner Therapy with injection of platelet-rich plasma
Clear aligner therapy with injection of platelet-rich plasma
干预措施: Platelet-rich plasma (Biological)
结局指标
主要结局
Measuring the amount of tooth movement in group of clear aligner therapy and group of clear aligners with injectable platelet-rich plasma by little's irregularity index
时间窗: Baseline, 3 weeks, and 6 weeks
Little's irregularity index is used to measure the amount of tooth movement by measuring the distance between each contact points in anterior teeth before injection and after injection
次要结局
未报告次要终点
研究者
Ali Mahmoud Ali Elhewaity
Dr
Al-Azhar University