Evaluation of effects of Injectable - Platelet Rich Fibrin and combination of Injectable -Platelet Rich Fibrin & Low Intensity Laser Therapy on the rate of canine retraction - A Randomized Controlled Trial.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Fibrin and combination of Injectable Platelet
研究概览
简要总结
Orthodontic treatment is a long process and it is one of the major concerns. To counteract this problem, there is a need to increase the rate of tooth movement. Various methods that can increase the rate of orthodontic tooth movement and reduce the treatment time, includes non-surgical methods like low intensity laser therapy, local injections of prostaglandins, 1, 25(OH)2D3 (the active form of vitamin D3), osteocalcin and Relaxin around the alveolar socket. Among this I-PRF & LILT are noninvasive options for accelerating the orthodontic tooth movement (OTM). Therefore, the aim of this study is to evaluate effects of I-PRF and combination of I-PRF & LILT on the rate of canine retraction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 15.00 Year(s) 至 25.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of either sex with age group of 15-25 years.
- •Angles class I or class II Division 1 malocclusion with Bimaxillary protrusion.
排除标准
- •Patients with previous history of orthodontic treatment Patient with canine having dilacerated roots.
- •Patients with impacted canine.
- •Patients with sign of gingival or periodontal disease.
- •Patients with metabolic disorders that leads to bone pathologies.
结局指标
主要结局
Fibrin and combination of Injectable Platelet
时间窗: •T0: at the start of canine retraction. | •T1: at 1 st month after the start of canine retraction. | •T2: at 2 nd month after the start of canine retraction. | •T3: at 3 rd month after the start of canine retraction. | •T4: at the end of canine retraction.
To evaluate effects of Injectable Platelet Rich
时间窗: •T0: at the start of canine retraction. | •T1: at 1 st month after the start of canine retraction. | •T2: at 2 nd month after the start of canine retraction. | •T3: at 3 rd month after the start of canine retraction. | •T4: at the end of canine retraction.
Rich Fibrin and Low Intensity Laser Therapy on
时间窗: •T0: at the start of canine retraction. | •T1: at 1 st month after the start of canine retraction. | •T2: at 2 nd month after the start of canine retraction. | •T3: at 3 rd month after the start of canine retraction. | •T4: at the end of canine retraction.
the rate of canine retraction
时间窗: •T0: at the start of canine retraction. | •T1: at 1 st month after the start of canine retraction. | •T2: at 2 nd month after the start of canine retraction. | •T3: at 3 rd month after the start of canine retraction. | •T4: at the end of canine retraction.
次要结局
- To compare effects of Injectable Platelet Rich(Fibrin & combination of Injectable Platelet Rich)