Acute rule out of non-ST segment elevation acute coronary syndrome in the (pre)hospital setting by HEART score assessment and a single point of care tropnin: the ARTICA randomized trial - ARTICA randomized trial

Radboud Universitair Medisch Centrum0 个研究点目标入组 866 人开始时间: 待定最近更新: 2024年4月15日

试验速览

暂无简介。

•Patients with symptoms suggestive for non ST-segment elevation acute coronary
•syndrome with symptom duration of at least two hours, a HEART score equal or
•less than 3 and a point of care troponin below the lower limit of the measuring

•- Patients with an acute ST elevation myocardial infarction
•- Patients presenting an obvious non-cardiac cause for the chest complaints who
•need evaluation at an emergency department, e.g. trauma, pneumothorax, sepsis,
•- Patients in comatose state, defined as an EMV <8
•- Patients with known cognitive impairment
•- Pregnancy or intention to become pregnant during the course of the study
•- Patients presenting cardiogenic shock, defined as: systolic blood pressure
•<90mmHg and heart rate >100 and peripheral oxygen saturation <90% (without
•oxygen administration)
•- Patients presenting with syncope
•- Patients presenting with signs of heart failure
•- Patients presenting with heart rhythm disorders and second or third degree
•atrioventricular block
•- Patients with known end-stage renal disease (dialysis and/or MDRD < 30 ml/min)
•- Patients without a pre-hospital 12-lead ECG performed or available
•- Patients suspicious of aortic dissection or pulmonary embolism
•- Patients with confirmed AMI, PCI or CABG <30 days prior to inclusion
•- Communication issues with patient/language barrier
•- Decision of a present general practitioner to evaluate the patient at ER
•- Decision of the consultant cardiologist to evaluate patient at the ER
•irrespective of HEART score
•- Any significant medical or mental condition, which in the Investigator*s
•opinion may interfere with the patient*s optimal participation in the study

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