Cost-effectiveness of minimal invasive spinal fusion compared to open fusion for patients with spinal stenosis with neurogenic claudication or radicular leg pain. - Cost-effectiveness of Minimal Invasive fusion (DOMINO)

eids Universitair Medisch Centrum0 个研究点目标入组 340 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•- Neurogenic claudication or radicular leg pain.
•- Complaints are due to MRI confirmed existence of lytic or degenerative spondylolisthesis of maximal 50% or Meyerding Grade II, or spinal stenosis accompanied by severe facet degeneration (grade 2 or 3 according to Weishaupt (Skeletal Radiol 1999; 28 (4):215-9), at one or two levels
•- Single or double level fusion indicated.
•- Insufficient response to conservative therapy (physical therapy, analgesic medications, or trans-foraminal corticosteroid injections) for at least 6 months.
•- Age is between and including 18-70 years.
•- Be able to understand the Dutch language and comprehend the questionnaires and patient information.
•- Patients signed informed consent.

•- Iatrogenic Spondylolisthesis or more than 50% or more than Meyerding Grade II.
•- Inflammatory arthritis, Osteoporosis or other metabolic bone disease to a degree that it would influence fusion.
•- Contraindication for surgery.

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