Effect of finger millet based dietary supplementation on gut microbiota composition and function in uncomplicated moderate acute malnutrition in under 5 children

ICMR National Institute of Nutrition0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年12月19日

试验速览

暂无简介。

•1.Only children aged 30 to 59 months (below 5 years) will be enrolled in the study
•2.Children detected for the first time (primary) with Moderate acute malnutrition (MAM) having weight-for-height z-score (WHZ) between -2 and -3 below the median of the WHO child growth standards. These are children who have never been previously diagnosed or received any treatment for undernutrition (based on anthropometry records maintained at Anganwadi centers).
•3.For Control or Apparently Healthy (AH) children, weight-for-height z-score (WHZ) should be between -1 and +1 of the medians of the WHO child growth standards.
•4.They also should never have been previously diagnosed or received any treatment for undernutrition

•1 Any congenital/acquired disorder affecting growth i.e. known case of trisomy-21 or cerebral palsy
•2.Children having Severe anemia ( <8mg/dl) as assessed by Hemocue (Model no. Hemocue Hb 301)
•3.Children with dietary caloric insufficiency (as assessed through 24-hour dietary recall method) will be excluded from the study
•4.History of diarrhea, severe acute respiratory illness (SARI) or any other serious ailment requiring hospital admission within a period of at least four weeks before fecal sample collection will not be included in the study
•5.Subjects who have consumed or will need to consume any antibiotics, probiotics, prebiotics, or any other products capable of drastically altering the gut microbiome, within a period of at least four weeks before enrolment in the study or anytime during the trial, will be excluded from the study
•6.Receiving concurrent treatment for another condition
•7.Requires use of medication or undergoes any medical procedure for treatment of any infection/condition during the feeding trial or follow up period of up to 6 months, that may alter the microbiota profile of the gut, will be excluded from the study

发起方

ICMR National Institute of Nutrition