EUCTR2008-000893-19-GB进行中（未招募）1 期
A randomised, double blind, placebo controlled, crossover trial of the adjuvant properties of imipramine for the overactive bladder. - RCT of adjuvant imipramine for the overactive bladder
Whittington NHS Trust0 个研究点目标入组 40 人开始时间: 2008年6月17日最近更新:
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
入选标准
- •1. Adults aged 18 years or older
- •2. Both males and females
- •3. Symptoms of frequency more than or equal to 8 per day; urgency with or without urge incontinence
- •4 On antimuscarinic montherapy for overactive bladder symptoms
- •4. Able to give informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1)<18 years
- •2)Inability to provide consent.
- •3)Current urinary infection as determined by >10 wbcs per ml onmicroscopy or 10^5 colony forming organisms on MSU.
- •4) History of mania.
- •5) Has taken monoamine oxidase inhibitors in the last 3 months.
- •6) Myocardial infraction in the previous 6 months.
- •7) Cadiovascular disease
- •8) History of cardiac arrythmias.
- •9) History of active liver disease
- •10) Deranged liver function tests.
- •11) Pregnant or breast feeding
- •12) Heart Block
- •13) Porphyria
- •14) Open angle glaucoma
- •15) Baldder cancer
- •16) Prostate cancer
- •17) Patients currently taking antidepressants with the exception of serotonin reuptake inhibitors or serotonin/noradrenaline reuptake inhibitors.
- •18) Hyperthyroidism
研究者
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