Effects of antibiotic prophylaxis on rates of early implant failure in dental implant surgery for adult patients: Randomized controlled clinical trial.

Master in Oral Surgery and Implantology, University of Granada0 个研究点目标入组 100 人开始时间: 2024年9月23日最近更新: 2024年9月30日

适应症

试验速览

阶段: 4 期
状态: 尚未招募
发起方
入组人数: 100
主要终点: Early implant failure[Defined by removal of the implant before prosthetic loading. <br>Patient clinic review at 7 days, 14 days, 30 days and 90 days. If early implant failure occurs outside of these periods, the patient will go to the faculty's operating room. Baseline, 7 days, 14 days, 30 days, 90 days<br>]

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

暂无简介。

研究设计

研究类型: Interventional
分配方式: Randomised controlled trial
主要目的: Treatment
盲法: Blinded (masking used)

入排标准

年龄范围: 18 Years 至 No limit（—）
性别: All

入选标准

•Patients 18 years and over• Subjects treated periodontally, if necessary, prior to placementof implants• Presence of sufficient bone and soft tissue that does not imply augmentation surgery in the moment of implant placement• Implants placed in a single surgical field

排除标准

•Patients who, due to their medical condition, require antibiotic prophylaxispostoperative (risk of endocarditis)• Patients undergoing head and neck radiotherapy less than 2 years ago• Diabetics (controlled and uncontrolled)• Allergic to penicillin• Patients treated with antiresorptive drugs• Pregnant or breastfeeding• Immunocompromised• Patients who are taking antibiotics for other reasons• Implants that require simultaneous bone regeneration• Implants in which immediate loading is carried out• Immediate implants

结局指标

主要结局

Early implant failure[Defined by removal of the implant before prosthetic loading. <br>Patient clinic review at 7 days, 14 days, 30 days and 90 days. If early implant failure occurs outside of these periods, the patient will go to the faculty's operating room. Baseline, 7 days, 14 days, 30 days, 90 days<br>]

次要结局

Presence of postoperatory infection [Postoperative pain and inflammation were evaluated daily on days 1 to 7 post-surgery using a VAS (0= no pain/swelling to 10=maximum imaginable pain/swelling), also recording the amount of anti-inflammatory/analgesic rescue medication taken each day. Presence of infection in the next control appointment (14 days, 30 days, 90 days). Baseline, days 1-7, 14 days, 30 days, 90 days post-surgery. ];Implant stability quotient (ISQ) values for primary and secondary implant stability[ISQ measured on the surgery day, and in day 90. baseline (surgery day) and 90 days post-surgery]

研究者

发起方

Master in Oral Surgery and Implantology, University of Granada

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