A Study to Observe the Change of the Biological Signal (Heart Rate) During the Combined Pituitary Stimulation Test
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Changes in Heart rate variability according to the types of pituitary adenoma
研究概览
简要总结
Several studies have been reported that heart rate is known to be associated with prognosis in chronic diseases and acute diseases. For example, a decrease in heart rate following myocardial infarction may lead to a higher mortality rate. It is also known to predict heart failure, diabetic neuropathy, and even depression.
The combined pituitary function test artificially induces hypoglycemia to observe the secretion of pituitary hormone. The degree of change in heart rate during hypoglycemia can predict the adequacy of the test, and heart rate can be changed according to the characteristic of the tumor. Also, the prognosis can be predicted based on this.
In our study, we used a licensed device approved by KFDA (Korea Food and Drug Administration) to measure heart rate variability in patients with pituitary adenoma.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Over 19 year old
- •Those with Normal blood pressure range:
- •90mmHg <systolic <140mmHg, 60mmHg <diastolic <100mmHg
- •Voluntary participants who visited Seoul St. Mary's Hospital
排除标准
- •Those who have been diagnosed with sleep disorders, diabetes, arrhythmia, psychiatric disorder, physical or mental breakdown, drug addicts
- •Diabetes, hypertension, cardiovascular disease diagnosed by taking a drug related to the disease
- •Pregnant or lactating women
- •Those who drank within 12 hours before participating in the trial
- •Those who are deemed inappropriate by clinical trial researchers
结局指标
主要结局
Changes in Heart rate variability according to the types of pituitary adenoma
时间窗: 5 month of initial recruit
次要结局
未报告次要终点
研究者
Dong Jun Lim
Professor
Seoul St. Mary's Hospital