Randomized comparison of the clinical Outcome of single versus Multiple Arterial grafts: the ROMA trial. - ROMA - WOMAN trial

Weill Cornell Medicine0 个研究点目标入组 250 人开始时间: 待定最近更新: 2024年4月15日

适应症

试验速览

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•primary isolated CABG patients with disease of the left main coronary artery or
•left anterior descending and the circumflex coronary system with or without
•disease of the right
•coronary artery. Coronary artery disease will be defined as a stenosis >= 70%
•based on coronary
•angiography, a FFR value <= 0.80 or iFr value <=0.89; a left main diameter
•stenosis >= 50%, left main IVUS
•MLA value <= 4.5 mm2, or equivalent OCT measurements will also be considered.

•Age <18, and men > 70 years • Planned single graft • Emergency operation •
•Preoperative myocardial infarction within 48 hours • Ejection Fraction (EF) <
•35% • Any concomitant cardiac or non-cardiac procedure • Previous cardiac
•operation • Preoperative severe end-organ dysfunction (dialysis, liver failure,
•respiratory failure), cancer or any co-morbidity that reduces life expectancy
•to less than 5 years. • Inability to use either the saphenous vein or both the
•right ITA and the RA as grafts • Anticipated need for coronary
•thrombo-endarterectomy. • Planned hybrid revascularization • Preoperative brain

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