NCT01335659已完成不适用
Relationship Between Fractional Flow Reserve and Coronary Angiography/Intravascular Ultrasound Parameters in Ostial Lesions: Major Coronary Ostial Lesions Versus Side Branch Ostial Lesions
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 77
- 主要终点
- lumen area
研究概览
简要总结
The investigators studied the relations between coronary angiography (CAG), intravascular ultrasound (IVUS) and fractional flow reserve (FFR) in coronary ostial lesions.
详细描述
Angiographic evaluation for ostial lesions is reported to be inaccurate in the assessment of the functional and clinical significance of a lesion. The investigators studied the relations between coronary angiography (CAG), intravascular ultrasound (IVUS) and fractional flow reserve (FFR) in coronary ostial lesions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 21 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 21-85
- •Presence of at least one obstructive coronary artery stenosis at coronary ostium as defined by:
- •Previous catheterization with any coronary ostium lesion 50% or greater
- •Ability and Willingness to provide informed consent
- •Ability and Willingness to perform required follow up procedures
排除标准
- •History of coronary artery bypass graft surgery
- •left main coronary ostial lesion
- •significant stenosis at proximal or distal part of coronary ostium lesion
- •ostial lesion related to infarcton
- •Creatinine>1.6 mg/dL or GFR<30 pre-procedure per institutional standards
- •Ejection fraction lower than 40%
- •Known Pregnancy
- •Arrhythmia
- •Contrast agent allergy that cannot be adequately premedicated
- •Patient not a candidate for IVUS and FFR
- •Inability or unwillingness to provide informed consent
- •Inability or unwillingness to perform required follow up procedures
结局指标
主要结局
lumen area
时间窗: 1 day
lumen area at ostial lesion
次要结局
- angiographic stenosis, % plaque area(1 day)
研究者
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