Intracardiac Flow Remodeling in Athletes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Evaluation of ventricular response to exercise training by echocardiography.
研究概览
简要总结
The uncertainty concerning the onset and the extent of cardiac remodeling in response to intensive training hinders medical evaluation by physician. A better knowledge of the physiology of cardiac adaptation to training will enable physicians to correctly determine whether observed patterns of cardiac remodeling are physiological or pathological. This prospective study proposes to assess in a trained-athlete population the cardiac remodeling in response to intensive exercise training. This study is observational, we do not interfere with athlete's training.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age > 18yrs old
- •Ability to give written consent for participating in the study
排除标准
- •Age < 18yrs old
- •Cardiac diseases, arterial hypertension, cardiac devices, diabetes, renal, liver or pulmonary failure
结局指标
主要结局
Evaluation of ventricular response to exercise training by echocardiography.
时间窗: Day 1
1. 2D- morphological and functional parameters of both left and right ventricles: * end-diastolic and end-systolic dimensions (cm) * left ventricular mass (g) * ventricular end-diastolic and end-systolic areas (cm²) * ventricular ejection fraction (%) * atrial volumes (ml) * diastolic indices by pulsed wave Doppler and tissue Doppler (cm/s) * myocardial deformation by speckle tracking (%) 2. 3D- morphological and functional parameters of both left and right ventricles: * ventricular full volumes (ml) * ejection fraction (%) 3. Intracardiac flow measurements by color Doppler M-mode: estimation of intra ventricular pressure gradients between the base and the apex (mmHg).
次要结局
- Evaluation of ventricular response to exercise training by electrocardiogram(Day 1)
- Sport and medical history questionnaire(Day 1)
研究者
Amir HODZIC
Medical Doctor
University Hospital, Caen