The Assessment of Curcuma Longa Potentials for Soft and Hard Tissue Healing in Fresh Extraction Sockets; Randomized Controlled Clinical Trial.
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Soft tissue healing
研究概览
简要总结
The study will be conducted on 30 patients with split mouth design patients will be divided into curcumin and PRF groups patients will have bilateral tooth extraction one side will receive curcumin/PRF and the other side will be control soft tissue healing and bone quality will be evaluated post-operative
详细描述
30 Patients will be collected from the outpatient clinic of the Department of Oral &Maxillofacial surgery, Faculty of Dentistry, MSA University, Cairo, Egypt
Eligibility criteria:
Inclusion Criteria for participants:
- Patients with bilateral badly decayed mandibular posterior tooth that need extraction.
- Patients free from any systemic disease
- Patients who approved to be included in the trial and signed the informed consent.
- Patients with no signs or symptoms of acute periapical\ periodontal infection.
- Adults aged between 18-50 years old.
Exclusion criteria for participants:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •1. Patients with bilateral badly decayed mandibular posterior tooth that need extraction.
- •2. Patients free from any systemic disease
- •Patients who approved to be included in the trial and signed the informed consent.
- •4. Patients with no signs or symptoms of acute periapical\ periodontal infection.
- •5. Adults aged between 18-50 years old.
排除标准
- •1. Patients who are allergic to Curcumin
- •Smoker patient
- •Patients receiving chemotherapy or radiotherapy.
- •Patients who refused to be included in the trial.
研究组 & 干预措施
Control
extraction socket .
干预措施: extraction socket (Other)
PRF Group
extraction socket and PRF
干预措施: PRF (Biological)
PRF Group
extraction socket and PRF
干预措施: extraction socket (Other)
Curcuma Longa Group
Extraction Socket and Curcuma Longa
干预措施: Curcuma Longa gel (Biological)
Curcuma Longa Group
Extraction Socket and Curcuma Longa
干预措施: extraction socket (Other)
结局指标
主要结局
Soft tissue healing
时间窗: 21 days after surgery
Healing index (change is being assessed)
次要结局
- Bone Density(3 months after surgery)
研究者
Rania Farouk Mohamed Abdulmaguid
Associate Professor Oral medicine and periodontology faculty of dentistry MSA university
October University for Modern Sciences and Arts