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临床试验/NCT05943405
NCT05943405已完成不适用

The Disease Severity In Patients With Psoriasis

Universitas Sebelas Maret1 个研究点 分布在 1 个国家目标入组 33 人开始时间: 2022年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
33
试验地点
1
主要终点
Gamma-Glutamyl Transferase

研究概览

简要总结

This observational study aims to evaluate new markers to predict disease activity in psoriasis. The main question is SGOT, SGPT, GGT, hs-CRP, and apo B related to disease severity in psoriasis.

详细描述

Psoriasis patients who had signed an informed consent were assessed for PASI scores and 5 cc of blood was drawn for GGT, hs-CRP, and apo B examinations. A PASI score is a tool used to measure the severity and extent of psoriasis. PASI is an acronym for Psoriasis Area and Severity Index.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Clinical diagnosis of Psoriasis

排除标准

  • Heart Failure
  • Diabetes Mellitus
  • Kidney Disease

结局指标

主要结局

Gamma-Glutamyl Transferase

时间窗: only in admission

Gamma-Glutamyl Transferase was check in admission, reference range for adults is 5 to 40 U/L (units per liter)

Apolipoprotein B

时间窗: only in admission

Apolipoprotein B (ApoB) is the primary apolipoprotein and is the carrier for the following lipids: chylomicrons, low-density lipoprotein ( LDL), very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), and lipoprotein. Unit used in mg/dL

High-sensitivity c-reactive protein

时间窗: only in admission

High-sensitivity C-reactive protein (hsCRP) is a marker of inflammation that predicts incident myocardial infarction, stroke, peripheral arterial disease, and sudden cardiac death. Unit used in mg/L

PASI

时间窗: only in admission

A PASI (The Psoriasis Area and Severity Index) score can range from 0 to 72

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Nurhasan Agung Prabowo, MD

Head of Hospital Research Unit

Universitas Sebelas Maret

研究点 (1)

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