Finding Good TEMporal PostOperative Pain Signatures (TEMPOS)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 428
- 试验地点
- 1
- 主要终点
- Measure postoperative pain scores change with respect to time
研究概览
简要总结
The purpose of this research study is to determine what causes pain after surgery to increase or decrease over time.
详细描述
Before surgery, study participants will be asked questions about age, gender, race/ethnicity, annual income, and education level. Study participants will also be questioned regarding prior pain experiences, their mood and how they think about pain. A small test tube of blood, a cheek swab or a saliva sample will be taken to see what genetic differences may influence individuals pain after surgery.
After surgery, study participants will be asked questions about their pain intensity while in the hospital. Additional information will be collected about the effects of pain medicine, and their recovery from surgery.
Following discharge from the hospital, study participants will be contacted monthly to confirm continued communication. Study participants will also be contacted six months after surgery, and asked to complete a final survey about their pain after surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 years of age or older
- •anticipated length of hospital stay of 72 hours or greater
- •expected post-operative survival greater than 6 months
排除标准
- •< 18 years of age
- •anticipated need for prolonged post-operative intubation (greater than 24 hours)
- •urgent or emergent surgical procedure
- •inability to understand or participate in questionnaires, surveys or data collection
结局指标
主要结局
Measure postoperative pain scores change with respect to time
时间窗: up to 7 days
Pain scores will be measured using previously established pain scale and Questionnaire
次要结局
- Measure timing patterns that may influence development of persistent postsurgical pain (PPP)(up to 6 months)
- Genetic testing(up to 1 day)
- Measure variables that contribute to postoperative pain scores(up to 6 months)