Measurement of anti-inflammatory resolvins and protectins in individuals with features of the metabolic syndrome compared with matched healthy controls, after omega-3 fatty acids alone and in combination with aspirin

Professor Trevor Mori0 个研究点目标入组 40 人开始时间: 2010年8月25日最近更新: 2020年1月13日

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•Men and post-menopausal women not taking hormone replacement therapy, aged 20-70 years, will be recruited from the general population by newspaper advertisements. Subjects will recruited on the basis of being untreated but having features of the metabolic syndrome using the criteria of the National Cholesterol Education Program Adult Treatment Panel III (NCEP: ATP III). They will be invited to participate if they have a waist circumference >102cm for males and >88cm for females and systolic blood pressure (SBP) >130 mmHg,
•Age and gender matched healthy control subjects will be recruited from the general population. Subjects will be included if in the age range 20 to 70 years with a waist circumference <102cm for males and <88cm for females and no other defining criteria for the metabolic syndrome.

•Smokers, history of cardiovascular or peripheral vascular disease, diabetes, renal disease, liver disease or taking anti-hypertensive agents, lipid lowering drugs, aspirin or non-steroidal anti-inflammatory drugs, omega-3 fatty acids or >2 fish meals /week.

发起方

Professor Trevor Mori