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临床试验/NCT06832995
NCT06832995进行中(未招募)不适用

Incidence and Risk Factors for Post-Anesthetic Morphine Titration in Recovery Room After Hip and Knee Arthroplasties: a Single-center Retrospective Study

Hôpital Privé Sévigné1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2024年4月1日最近更新:
干预措施
相关药物

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
300
试验地点
1
主要终点
morphine titration

研究概览

简要总结

Despite the use of multimodal analgesia combining nerve block (NB) and systemic analgesia, intravenous (IV) morphine titration in the post-anesthetic care unit (PACU) after total hip (THA) and knee (TKA) arthroplasty is required to relieve early moderate-to-severe pain. Sedation occurrence during titration and a VAS score higher than 60/100mm are two independent risk factors for postoperative pain during hospitalization.

The association of NB and multimodal analgesia constitutes the reference in evidence-based recommendations. An adductor or femoral triangle block, alone or associated with periarticular infiltration, is recommended during TKA. During THA, NB associated with surgical periarticular infiltration improves analgesia and rehabilitation This study aims to identify the incidence and risk factors of morphine titration in PACU after lower limb arthroplasty performed by 5 experienced surgeons and using a multimodal analgesic procedure

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Total hip arthroplasty
  • Total Knee Arthroplasty
  • Uni-compartmental knee arthroplasty (UKA)

排除标准

  • Bilateral surgery Surgical revision Hip fracture surgery Other osteoarticular procedure(s) associated to hip/knee arthroplasty Refusal to use data Contra-indication of paracetamol, ketoprofen and dexamethasone

研究组 & 干预措施

group T: IV morphine administered during the PACU stay

干预措施: IV morphine administered during the PACU stay (Drug)

结局指标

主要结局

morphine titration

时间窗: after surgery, in the post-anesthetic care unit

次要结局

未报告次要终点

研究者

发起方
Hôpital Privé Sévigné
申办方类型
Other
责任方
Sponsor

研究点 (1)

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