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临床试验/CTRI/2025/06/088016
CTRI/2025/06/088016招募中4 期

A comparative clinical study to evaluate the role of individualised homoeopathic remedy with and without Chelidonium Q in the management of Osteoarthritis

Venkateswara Homoeopathic Medical College and Hospital , Chennai1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年10月6日最近更新:

试验速览

阶段
4 期
状态
招募中
发起方
入组人数
60
试验地点
1
主要终点
WOMAC score

研究概览

简要总结

Background: Osteoarthritis (OA) is a long-term joint condition thatcauses pain, stiffness, and reduced mobility, often affecting a person’s dailylife. Homoeopathy offers a gentle, holistic approach to managing such chronicconditions. Chelidonium Majus Q, a well-known homoeopathic mother tincture, hastraditionally been used to address hepatic disorders, this study explores howeffective Chelidonium Majus Q when given along with individualized Homoeopathicmedicine in review with Homoeopathic Materia medica is in relieving thesymptoms of Osteoarthritis of the knee.

Objective: This study is intended to determine and evaluate theeffectiveness of Chelidonium Majus in mother tincture form in reduction of painand stiffness in patients with Osteoarthritis, and to compare the WOMAC scores and Visual Analogue Scale of both groups to determine statistical significance.

Methodology: This Randomized clinical study of 60 cases involving twogroups, 30 cases each. GROUP 1 cases managed with individualized homoeopathicmedicine and Chelidonium majus Q, GROUP 2 cases managed with individualizedhomoeopathic medicine only. The results obtained will be statisticallyanalyzed and evaluated by using Paired ‘T’ test in order to determine theeffectiveness of Chelidonium majus Q in symptomatic relief of Osteoarthritis ofthe knee. This study provides evidence to say that, Chelidonium majus in theform of mother tincture have significant results in lowering the pain and jointstiffness, and improves the mobility of the affected knee in Osteoarthritispatients.

 Expected Outcome: This study anticipates demonstrating that Patientsadministered with Chelidonium majus q along with Individualized homoeopathicmedicine will show significant reduction in pain and stiffness of joint, which  is assessed through WOMAC scale and Visual Analogue Scale

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant Blinded

入排标准

年龄范围
50.00 Year(s) 至 75.00 Year(s)(—)
性别
All

入选标准

  • patients diagnosed with Osteoarthritis of Knee with Western Ontario McMaster Universities Arthritis Index score of more than
  • Patients with Visual Analogue Scale of more than 4.

排除标准

  • Rheumatoid arthritis, psoriatic arthritis, Gout.
  • patients with any other disease affecting mobility, patients with severe systemic illness such as liver and kidney dysfunction, diabetes, cardio vascular disease, patients on long term NSAIDS or steroids,.

结局指标

主要结局

WOMAC score

时间窗: Baseline and after 12 weeks

次要结局

  • Visual Analogue Score, joint stiffness and physical functions of the patient(baseline ,2weeks, 4 weeks, 6 weeks,8weeks, 10 weeks, 12 weeks)

研究者

发起方
Venkateswara Homoeopathic Medical College and Hospital , Chennai
申办方类型
Private medical college

研究点 (1)

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