A comparative clinical study to evaluate the role of individualised homoeopathic remedy with and without Chelidonium Q in the management of Osteoarthritis
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- WOMAC score
研究概览
简要总结
Background: Osteoarthritis (OA) is a long-term joint condition thatcauses pain, stiffness, and reduced mobility, often affecting a person’s dailylife. Homoeopathy offers a gentle, holistic approach to managing such chronicconditions. Chelidonium Majus Q, a well-known homoeopathic mother tincture, hastraditionally been used to address hepatic disorders, this study explores howeffective Chelidonium Majus Q when given along with individualized Homoeopathicmedicine in review with Homoeopathic Materia medica is in relieving thesymptoms of Osteoarthritis of the knee.
Objective: This study is intended to determine and evaluate theeffectiveness of Chelidonium Majus in mother tincture form in reduction of painand stiffness in patients with Osteoarthritis, and to compare the WOMAC scores and Visual Analogue Scale of both groups to determine statistical significance.
Methodology: This Randomized clinical study of 60 cases involving twogroups, 30 cases each. GROUP 1 cases managed with individualized homoeopathicmedicine and Chelidonium majus Q, GROUP 2 cases managed with individualizedhomoeopathic medicine only. The results obtained will be statisticallyanalyzed and evaluated by using Paired ‘T’ test in order to determine theeffectiveness of Chelidonium majus Q in symptomatic relief of Osteoarthritis ofthe knee. This study provides evidence to say that, Chelidonium majus in theform of mother tincture have significant results in lowering the pain and jointstiffness, and improves the mobility of the affected knee in Osteoarthritispatients.
Expected Outcome: This study anticipates demonstrating that Patientsadministered with Chelidonium majus q along with Individualized homoeopathicmedicine will show significant reduction in pain and stiffness of joint, which is assessed through WOMAC scale and Visual Analogue Scale
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 50.00 Year(s) 至 75.00 Year(s)(—)
- 性别
- All
入选标准
- •patients diagnosed with Osteoarthritis of Knee with Western Ontario McMaster Universities Arthritis Index score of more than
- •Patients with Visual Analogue Scale of more than 4.
排除标准
- •Rheumatoid arthritis, psoriatic arthritis, Gout.
- •patients with any other disease affecting mobility, patients with severe systemic illness such as liver and kidney dysfunction, diabetes, cardio vascular disease, patients on long term NSAIDS or steroids,.
结局指标
主要结局
WOMAC score
时间窗: Baseline and after 12 weeks
次要结局
- Visual Analogue Score, joint stiffness and physical functions of the patient(baseline ,2weeks, 4 weeks, 6 weeks,8weeks, 10 weeks, 12 weeks)
