跳至主要内容
临床试验/NCT02377128
NCT02377128Unknown不适用

Ovarian Reserve Following Bilateral Salpingectomy Versus Tubal Ligation During Cesarean Section

Wolfson Medical Center0 个研究点目标入组 45 人开始时间: 2015年3月最近更新:
适应症

试验速览

阶段
不适用
入组人数
45
主要终点
Change from baseline in Anti Mullerian hormone (AMH) levels ng/mL at 8 weeks

研究概览

简要总结

The aforementioned study was designed to evaluate short term ovarian reserve as assessed by anti-Mullerian hormone(AMH) levels following bilateral salpingectomy versus tubal ligation, as part of cesarean sections performed in women requesting future sterilization. The investigators aim to recruit 3 groups of 15 women undergoing elective cesarean section at the investigators' institution, 2 of which request sterilization (allocated to tubal ligation or bilateral salpingectomy) and one undergoing solely cesarean section. The groups will have blood drawn for AMH prior to the procedure and at a post-operation visit 8 weeks following. This is preformed in light of validated data offering better sterilization and possible diminished future risk of ovarian cancer with salpingectomy. Also, is has been proved to be just as safe as tubal ligation. This will be performed as a randomized controlled trial.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

性别
Female
接受健康志愿者

入选标准

  • Women undergoing elective cesrean section at the investigators' institution, requesting sterilization, willing to have blood withdrawn for AMH levels prior to surgery, willing to participate in 8 weeks post-operation follow up with blood withdrawn

排除标准

  • Non-elective cesarean section, non willing to have blood withdrawn or participate in follow up, prior salpingectomy, prior premature ovarian failure/egg donation

结局指标

主要结局

Change from baseline in Anti Mullerian hormone (AMH) levels ng/mL at 8 weeks

时间窗: Baseline and 8 weeks following surgery

AMH levels

次要结局

未报告次要终点

研究者

申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Hadas Ganer Herman

Dr.

Wolfson Medical Center

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