A Blood Test to Identify Persons at Risk of Developing Depression or Bipolar Disorder
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Assessment of classification accuracy of protein concentrations in dried blood spots for distinguishing between bipolar disorder and depression
研究概览
简要总结
This study aims to identify signs of depression and bipolar disorder by measuring changes of certain molecules (biomarkers) that can be detected in dried blood spots. Our goal is to use these biomarkers to develop a diagnostic test to enable early treatment, which can lead to better patient outcomes.
详细描述
Bipolar disorder and major depression are serious mental health conditions that have a devastating impact on patients, their families and friends, and society. Currently, no laboratory test exists for these disorders. We are trying to develop a molecular test based on blood spots (small spots of blood obtained from patients' fingertips that have been dried on special paper). Volunteers take part by filling out the questionnaire at www.spot-depression.org. They may then be selected to provide a dried blood spot, which can be collected at home using a kit that will be mailed to their address.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Residing in the United Kingdom
- •Over 18 years of age
排除标准
- •Pregnant or breastfeeding
- •Presence of blood-borne infection
结局指标
主要结局
Assessment of classification accuracy of protein concentrations in dried blood spots for distinguishing between bipolar disorder and depression
时间窗: Baseline (at enrollment); no follow-up
Comparison of protein concentrations in dried blood spots between patient groups and controls
时间窗: Baseline (at enrollment); no follow-up
次要结局
未报告次要终点
研究者
Jordan Ramsey
Postdoctoral researcher
University of Cambridge