NCT05596656已完成不适用
IgE-mediated Allergies Among Type 1 Diabetes Mellitus Children, Single Centre Observational Study
Mansoura University Children Hospital1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2018年2月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- positive skin prick test
研究概览
简要总结
an interviewer-administrated questionnaire was designed to take history of allergy in diabetic child come to outpatient clinic fulfilling inclusion criteria and used to collect data. Skin prick testing was performed to all diabetic children with history of allergy. Laboratory assessment of Serum Total IgE, IL5 and eosinophils%.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 2 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children with at least 2 Years duration of diabetes diagnosed by Criteria for the diagnosis of diabetes mellitus (ISPAD 2018) that include:
- •Classic symptoms of diabetes or hyperglycemic crisis, with plasma glucose concentration ≥11.1 mmol/L (200 mg/dL).
- •Fasting plasma glucose ≥7.0 mmol/L (≥126 mg/dL). Fasting is defined as no caloric intake for at least 8 hours.
- •Two-hour post load glucose ≥11.1 mmol/L (≥200 mg/dL) during an oral glucose tolerance test (OGTT).
- •HbA1c ≥6.5%.
排除标准
- •presence of other chronic disease associated with DM.
结局指标
主要结局
positive skin prick test
时间窗: 20 minutes
a wheal ≥3 mm diameter more than negative control for detection of specific IgE to one or more of common aeroallergens.
次要结局
未报告次要终点
研究者
Engy Osman Ahmed
assistant professor
Mansoura University Children Hospital
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Evaluation of the Role of IgE Responses to Der p 1 and Der p 2 in Chinese House Dust Mite-Allergic PatientsAtopic DermatitisAsthmaAllergic RhinitisConjunctivitisNCT04984941Second Affiliated Hospital, School of Medicine, Zhejiang University100
已完成
不适用
online survey Kinderdiabeteslotse-SHE10Type 1 diabetes mellitusDRKS00024940Damp Stiftung179
进行中（未招募）
不适用
The Melbourne Atopy Cohort Study (MACS): A Randomised controlled trial of a partially hydrolysed whey and a soy formula for the prevention of allergic disease.Allergic manifestationsEczemaAsthmaAllergic rhinitisAtopyAllergic manifestationsEczemaAllergic rhinitisAtopyInflammatory and Immune System - AllergiesDiet and Nutrition - Other diet and nutrition disordersAsthmaACTRN12609000734268estec Ltd,620
Unknown
不适用
Additional Autoimmune Diseases With Type 1 Diabetes in Pediatrics at Diabetes Diagnosis and During Follow-upAutoimmune DiseasesHashimoto DiseaseGraves DiseaseAddison DiseaseType 1 DiabetesVitiligoCeliac DiseaseNCT04789993Central Hospital, Nancy, France250
已完成
不适用
Cohort Study of Patients With Type 1 DiabetesStructured EducationType 1 Diabetes MellitusNCT03610984Second Xiangya Hospital of Central South University2,110