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临床试验/NCT07038291
NCT07038291已完成不适用

Factors Associated With Extubation Failure in Kanigara ICU (Intensive Care Unit) RSUPN Dr. Cipto Mangunkusumo

Indonesia University1 个研究点 分布在 1 个国家目标入组 156 人开始时间: 2025年3月1日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
156
试验地点
1
主要终点
Factors Associated with Extubation Failure analyzed using logistic regression analysis

研究概览

简要总结

Extubation is the final stage after patients undergo weaning procedure from mechanical ventilation in the ICU. Extubation failure followed by reintubation is associated with worse patient outcomes, including prolonged length of stay, increased risk of pulmonary infections, need for tracheostomy, higher healthcare costs, and increased mortality. Careful evaluation of various risk factors for extubation failure must be considered, therefore the extubation readiness guideline or checklist is essential before making the decision to extubate. This study aimed to identify factors associated with extubation failure in Kanigara ICU patients. This was a case-control study using secondary data from medical records of ICU patients who underwent extubation between January 2021 until August 2024. Variables analyzed included Glasgow Coma Scale (GCS) score, Arterial Blood Gas (ABG) results, hemodynamics, ventilator settings, airway protection ability, fluid balance, and airway-related problems. Bivariate and multivariate using logistic regression analyses were conducted to identify factors associated with extubation failure.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patient age 18 years old or more were intubated in Kanigara ICU RSCM more than 24 hours

排除标准

  • Dead or needed tracheostomy before extubation, or reintubated for surgical procedure

结局指标

主要结局

Factors Associated with Extubation Failure analyzed using logistic regression analysis

时间窗: From January 2021 to August 2025

Factors assessed were GCS score, hemodynamics, fluid balance, BGA results, airway protection ability, and airway related problems. Data were taken from medical records.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Adhrie Sugiarto

Head of Anesthesiology and Intensive Care Study Program

Indonesia University

研究点 (1)

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