a Non-invasive Device for the Detection, Diagnosis and Screening of Oral Pathology
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 77
- 试验地点
- 2
- 主要终点
- Diagnostic Tool
研究概览
简要总结
The overall objective of this work is to identify changes in the optical properties of oral tissues to develop a non-invasive tool for the detection, diagnosis and screening of oral pathology so that treatment can be provided at the earliest possible time.
详细描述
Specifically, we will be obtaining optical spectroscopic data using a fiber optic contact probe that exploits elastic-scattering spectroscopy and fluorescence spectroscopy. Both of these technique have independently shown to provide signatures for the onset of cancer, with varied success. The purpose of this effort is to combine the two techniques and develop and understanding of the signatures obtained in both normal and abnormal oral tissue with simultaneous collection of these optical signatures.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •adult over 18 years of age
排除标准
- •younger than 18 years of age
结局指标
主要结局
Diagnostic Tool
时间窗: 4 weeks
Fluorescence/Elastic Scattering Spectroscopy Oral tissue measurement
次要结局
未报告次要终点
研究者
Beckman Laser Institute and Medical Center
Petra Wilder-Smith, DDS., PhD., Professor, Director of Dentistry
University of California, Irvine