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临床试验/DRKS00020981
DRKS00020981招募中未知

se of mechanical insufflation-exsufflation for ineffective cough in diseases of the peripheral or central nervous system - MEDINE

Koninklijke Philips N.V.0 个研究点目标入组 100 人开始时间: 2021年2月11日最近更新:
适应症

试验速览

阶段
未知
状态
招募中
入组人数
100

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Randomized controlled study
盲法
Open (masking not used)

入排标准

年龄范围
18 Years 至 100 Years(—)
性别
All

入选标准

  • Existent severe illness from the neurological or neurosurgical spectrum defined as early rehabilitation Barthel Index (ERBI) < 35 points, a cough deficiency and/or retention of secretion, identified by peak cough flow <270l/min. or diagnosed by application of the airway clearance score (ACS) >7 or cough >1 on ACS (Coplin et al. 2000, Windisch et al. 2017, Tanwar et al. 2019)

排除标准

  • Age <18 years, known bullous pulmonary emphysema, presence of pneumothorax during current clinical treatment or instable sternum.
  • Amyotrophic lateral sclerosis as well as other progressive neuromuscular disorders and paraplegia, continous intracenous sedation, orally intubated patients, expected death on the ICU

研究者

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