Mechanical In-Exsufflation for the prevention of ventilator-associated pneumonia in ICU : A Retrospective cohort study
Not Applicable
- Conditions
- critically ill patients
- Registration Number
- JPRN-UMIN000033292
- Lead Sponsor
- Chiba University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 689
Inclusion Criteria
Not provided
Exclusion Criteria
1) Aspiration or community-acquired pneumonia, provision of mechanical ventilation for < 48 h 2) Pneumothorax and pneumomediastinum, chronic obstructive pulmonary disease with bulla 3) Severe cardiovascular failure 4) Active alveolar hemorrhage 5) The patients had sustained any injury or developed any complication 6) Patients younger than 7 years 7) Patients were received rehabilitation less than 5 days
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome of our study is incidence of VAP, defined as pneumonia developing in a person who has been on mechanical ventilation (MV) for at least 48 hours and in term of MV.
- Secondary Outcome Measures
Name Time Method Infection-related Ventilator-Associated Complication (IVAC), the duration of MV, length of stay in ICU, mortality, the number of VAP/MV duration, Max clinical pulmonary infection score, bronchoscopy, bronchoscopy/MV duration,the event of bronchial obstruction (the event was oxyhemoglobin saturations of < 90%), the event of bronchial obstruction/duration of MV. antibiotic use day (with suspected VAP), antibiotic use day/duration of MV