Evaluation of Periapical Healing after Endodontic Microsurgery Using Different Retrograde Filling Materials With or Without Platelet Rich Fibrin - An In Vivo Study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- The purpose of this study is the Evaluation of periapical healing of the lesion after an endodontic microsurgery with different retrograde filling materials, with or without Platelet Rich Fibrin (PRF) autologous material.
研究概览
简要总结
The purpose of this study is the Evaluation of periapical healing of the lesion after an endodontic microsurgery with different retrograde filling materials, with or without Platelet Rich Fibrin (PRF) autologous material.
Total of 60 subjects with lesion not responding to conventional root canal treatment will be selected and endodontic microsurgery will be done. Retrograde root preparation will be done and subjects will be randomly divided into 4 groups of 15 members each based on the root end filling materials. Different retrograde filling materials(MTA, Biodentine) will be used with or without platelet rich fibrin.
wound healing will be evaluated radiographically by measuring the volume of the lesion using CBCT after 12 months post operation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 25.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Endodontic lesions not responding to conventional root canal treatments 2.Non-contributory medical history (ASA class I and class II) 3.Lesion involving 1-3 roots 4.Overfilled canals 5.Separated instrument in the apical half 6.Ledge formation or transportation in the canal 7.Anatomically complex root canal configurations.
排除标准
- •1.Medically compromised patient (ASA class III to class VI) 2.Fractured tooth 3.Periodontally compromised patients 4.Through and through defects 5.Close Proximity to critical anatomical structures.
结局指标
主要结局
The purpose of this study is the Evaluation of periapical healing of the lesion after an endodontic microsurgery with different retrograde filling materials, with or without Platelet Rich Fibrin (PRF) autologous material.
时间窗: 1 week | 3 months | 6 months | 12 months
次要结局
- The purpose of this study is the Evaluation of periapical healing of the lesion after an endodontic microsurgery with different retrograde filling materials, with or without Platelet Rich Fibrin(1 week)