Radiofrequency-based Speckle Tracking Echocardiography to Evaluate Diastolic Function
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Early Diastolic Mitral Annular Velocity (E-prime) Using Tissue Doppler
研究概览
简要总结
The purpose of this study is to evaluate a novel ultrasound system's ability to assess the relaxing properties of the heart compared to current techniques.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled to undergo a clinically indicated left heart cardiac catheterization will be recruited for the study.
排除标准
- •Suspected acute ST elevation myocardial infarction.
- •Acute coronary syndrome with active ongoing chest pain
- •Known or suspected acute aortic dissection
- •Known or suspected cardiac tamponade
- •Known history of unoperated constrictive pericarditis
- •Known or suspected severe aortic stenosis or severe mitral regurgitation
- •Heart rhythm other than sinus rhythm on pre-cath EKG
- •Age < 18 years old
- •Unable to provide informed consent
结局指标
主要结局
Early Diastolic Mitral Annular Velocity (E-prime) Using Tissue Doppler
时间窗: Assessed from echo obtained at time of enrollment
E-prime is a conventional commonly-used parameter of diastolic function. Higher values of E-prime typically reflect better diastolic function.
Diastolic Circumferential Strain Rate During Isovolumic Relaxation
时间窗: Assessed from echo obtained at time of enrollment
Diastolic circumferential strain rate during isovolumic relaxation is a novel measure of diastolic function that measures the rate of relaxation of the left ventricle during the interval of isovolumic relaxation (the period of active relaxation). We would expect that a higher value reflects better relaxation, and better diastolic function.
次要结局
未报告次要终点
研究者
Theodore J. Kolias
Associate Professor
University of Michigan