JPRN-UMIN000032784招募中1 期
Phase I/II study of preoperative treatment with XELOXIRI(CPT-11, L-OHP, capecitabine) with Cetuximab in patients with RAS wild type-advanced colorectal cancer - NAC XELOXIRI+Cetuximab in patients with advanced colorectal cancer
Sapporo Medical University School of Medicine Department of Surgery, Surgical Oncology and Science0 个研究点目标入组 48 人开始时间: 2018年5月30日最近更新:
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 48
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1) Any major surgical treatments within 4 weeks. 2) Prior chemotherapy or radiotherapy. 3) Pulmonary fibrosis or interstitial pneumonia. 4) Watery stool or diarrhea. 5) Active infection and inflammation or HBs antigen positive. 6) uncontrollable heart failure, renal failure, peptic ulcer, intestinal paralysis, ileus and diabetes mellitus. 7) synchronous or metachronous (within 3 years) malignancy other than carcinoma in situ 8) Pregnant women, possibly pregnant women, wishing to become pregnant, and nursing mothers. Men with no intention to practice birth control. 9) Severe mental disease. 10) History of the severe hypersensitivity. 11) Patients homozygous for UGT1A1*28, or UGT1A1*6, or heterozygous for both UGT1A1*28 and UGT1A1*6. 12) CTCAE v4.0>Grade1 of peripheral neuropathy. 13) Inadequate physical condition, as diagnosed by primary physician.
研究者
相似试验
进行中（未招募）
1 期
Phase II study of pre-operative treatment with external radiotherapy plus panitumumab in operable locally advanced rectal cancer (favourable and intermediate prognostic group) (RaP Study/STAR-03)Operable locally advanced rectal cancerMedDRA version: 14.1Level: LLTClassification code 10038019Term: Rectal adenocarcinomaSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)EUCTR2011-000649-20-ITFONDAZIONE DELL'ISTITUTO TOSCANO TUMORI92
已完成
不适用
Pilot study of preoperative chemotherapy of XELOX+ Bevacizumab in patients with locally-advanced lower rectal cancerRectal cancerJPRN-UMIN000003219Multicenter Clinical Study Group of Osaka, Colorectal Cancer Treatment Group20
招募中
2 期
Assessment of the Efficacy of Preoperative Exemestane Therapy for Endocrine-sensitive Postmenopausal Breast Cancer (SBCCSG-23)Breast cancerJPRN-UMIN000006453PO Saitama Breast Cancer Clinical Study Group (SBCCSG)60
已完成
2 期
Assessment of the Efficacy of Preoperative Exemestane Therapy for Endocrine-sensitive Postmenopausal Breast Cancer (SBCCSG-10)JPRN-UMIN000000802Saitama Breast Cancer Clinical Study Group (SBCCSG)23
招募中
2 期
Phase2 trial of Preoperative chemotherapy with XELOX prus Bv for resectable liver metastases from colorectal cancercolon cancerJPRN-UMIN000007931Sano HospitalGastrointestinal Center30