ACTRN12611000778987招募中2 期
Evaluation of Captopril and Nifedipine in Treatment of Hypertension in Children with Post-streptoccal Acute Glomerulonephritis with Hypertension- A Randomized Control Trial
niversiti Sains Malaysia (USM)0 个研究点目标入组 40 人开始时间: 2011年7月26日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 1 Years 至 12 Years（—）
- 性别
- All
入选标准
- •All patients with clinical signs and symptoms PSAGN with hypertension (Blood Pressure of > 95 percentile of their respective height, age and gender) with the age between 1 year old to 12 years old, weight of 10 kg to 50 kg.
- •Clinical sign and symptoms of PSAGN includes history and clinical findings of facial puffiness and hematuria (urine RBC detected), decreased urine output or symptomatic hypertension. It preceded with history of impetigo or pharyngitis. Blood investigations includes complement levels, throat swab, positive ASOT or anti-DNAase.
排除标准
- •1)Patients non post-streptococcal AGN i.e: SLE with Lupus Nephritis, Nephrotic syndrome, etc
- •2)Patients with PSAGN without hypertension (defined as BP > 95 percentile according to height, age and gender).
- •3)Encephalopathic patients defined as having seizures, severe headache and having fundoscopy changes that needs urgent antihypertensive or intravenous antihypertensives.
- •4)Second episode of PSAGN with hypertension.
- •5)Other causes of elevated BP i.e Essential Hypertension, Phaeochromocytoma
- •6)Patients with known renal problems
研究者
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