跳至主要内容
临床试验/NCT03484052
NCT03484052已完成不适用

Place of Jugular Ultrasound in the Evaluation of the Volemia by a Clinician Doctor in Routine Care (JUVIA)

Rennes University Hospital2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2018年5月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
20
试验地点
2
主要终点
Evaluation of the volemia

研究概览

简要总结

Interventional study with minimal risks and constraints, prospective, monocentric.

详细描述

To appreciate the volemia of a patient is a frequent problem in hospital in various situations: renal insufficiency, dyspnea, dysnatremia, etc. The aging of the population, the chronicity of pathologies, overweight among other causes can make it difficult to assess the volume of the disease by the clinic alone. The consequences of a poor evaluation are delayed management and possible iatrogeny.

New discrimination markers have emerged to help the clinician such as "brain natriuretic peptide (BNP)" in dyspnea, and especially transthoracic echocardiography (TTE) assessing filling pressures with a high potency. discrimination. In current practice the TTE has unequal accessibility, and requires trained practitioners. It is difficult to have an TTE performed for all patients where the question arises.

Just as an assessment of the initial volemia is often necessary, there are few objective monitoring criteria. One can quote the variation of the weight or the evolution of certain biological parameters but none is completely specific.

A new marker has been described for a few years: jugular ultrasound. Better accessibility (requires only a probe of 7-9Hz, possibly 5Hz), it can indeed be performed by any practitioner in less than a minute. The jugular distension is a reflection of cardiac pre-load and can be correctly estimated by ultrasound. It has been shown that cardiac decompensated patients have dilated jugular veins compared to a reference population. A low cohort also demonstrated the presence of jugular ultrasound distension in the absence of clinical distension.

In a US study, 119 patients admitted to the emergency department for dyspnea had a sensitivity of 99% for a specificity of 59% for trans-jugular ultrasound in cardiogenic edema.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Major patient;
  • Requiring a transfusion of 2 or more red blood cells in a routine care situation (transfusion programmed in the context of a day hospital or a traditional hospitalization, except in cases of massive bleeding);
  • Affiliate or beneficiary of a social protection scheme;
  • Having given his written consent.

排除标准

  • Patient with clinical or biological criteria for admission to intensive care as defined in the 1999 US ICU Practice Guidelines;
  • Major persons subject to legal protection (legal safeguards, guardianship, tutorship), persons deprived of their liberty;
  • Pregnant or lactating woman

结局指标

主要结局

Evaluation of the volemia

时间窗: Baseline

Variation in height of the area where the right jugular vein collapses in centimeters from the angle of Louis.

次要结局

  • Transfusion tolerance(Day 3)
  • Semi-quantitative measurement variation in the height of the zone where the right jugular vein colludes(Baseline)
  • Interobserver variability(Baseline)

研究者

发起方
Rennes University Hospital
申办方类型
Other
责任方
Sponsor

研究点 (2)

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