Comparison of total intravenous anesthesia(TIVA) with propofol and inhalation anesthesia with isoflurane in patients undergoing posterior lumbar fusion surgery: a randomized clinical trial

Hamedan University of Medical Sciences0 个研究点目标入组 66 人开始时间: 待定最近更新: 2024年8月26日

适应症

试验速览

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•Candidate patients for posterior fusion surgery of lumbar vertebrae with pedicle screw fixation method
•Patients who will have only 3 to 5 levels of lumbar spine fusion
•Willingness and consent to participate in the study
•Age between 18 and 65 years
•American Society of Anesthesiologists (ASA) Class I-II physical status
•Body mass index (BMI) less than 35 kg/m2

•Trauma patients
•Allergy to anesthetics used in the study
•Patients with severe chronic diseases (cardiovascular, respiratory, nervous, liver, kidney, electrolyte disorders)
•patient with uncontrolled blood pressure
•History of drug use
•Patients who receive medication or liquid therapy outside of routine before, during and after surgery
•History of bleeding disorders and treatment with anticoagulants
•Excessive bleeding (more than MABL)
•Women if they are menstruating
•Abnormal coagulation profile (platelet count less than 50x103/µL, PTT greater than 50 seconds, or INR greater than 1.3 on preoperative testing)
•Patients with a history of frequent nausea and vomiting and taking antiemetics in the 24 hours before surgery
•Patients with mental disorders and mental retardation, dementia or schizophrenia
•Recent brain surgery or cerebrovascular accidents

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