KCT0007916已完成未知
The Efficacies and Safeties of a 0.05% Cyclosporine Nanoemulsion and a 0.1% Cyclosporine Cationic Emulsion
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 105
研究概览
简要总结
The corneal staining scores and the TBUT and Schirmer test results showed that both groups showed significant improvements. The corneal staining scores significantly (and similarly) decreased in both groups. In the test group, the TBUT showed significant prolongation after 1 month of treatment and the Schirmer test score increased significantly after 3 months. Both groups reported less ocular discomfort and better compliance with drug use at 3 months than 1 month; the control group demonstrated a significant decrease in ocular discomfort at 3 month
研究设计
- 研究类型
- Observational Study
入排标准
- 年龄范围
- 30(Year) 至 57(Year)（—）
- 性别
- All
入选标准
- •1. age above 19 years
- •2. Patients diagnosed with moderate to severe dray eye disease
- •- ocular staining score = 3 or
- •- TBUT =10 sec
- •3. possible to follow-up more than 3 monts
- •4. the patient who agree to participate in the study voluntarily
排除标准
- •1. patients using cyclosporine or used within 1 month
- •2. patients with active ocular infection such as Stevens-Johnson syndrome
- •3. history of corneal transplantation or neurotrophic keratitis
- •4. patients with ocular disease which can affect the result of study
- •5. patients with allergic reaction to cyclosporine
研究者
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