NCT00528138已完成不适用
Prospective Study Comparing Hyperbilirubinemia, CRP, White Blood Cell Count, and Other Clinical Parameters for the Preoperative Diagnosis of Perforated Acute Appendicitis
Cirujanos la Serena1 个研究点 分布在 1 个国家目标入组 132 人开始时间: 2007年10月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 132
- 试验地点
- 1
研究概览
简要总结
It has recently been published that hyperbilirubinemia is a reliable marker for the preoperative diagnosis of perforated acute appendicitis.
The investigators believe, based on their own previous publications, that C-reactive protein (CRP) with or without a white blood cell count and some other clinical parameters, are more specific markers for the preoperative diagnosis of perforated acute appendicitis.
The purpose of this study is to prospectively compare the specificity and sensitivity of hyperbilirubinemia CRP, white blood cell count and other clinical parameters for the preoperative diagnosis of acute appendicitis.
详细描述
- Previously validated appendicitis score
- Time from onset of symptoms to diagnosis and to surgery
- Laboratory values: WBC, CRP, liver function test
- SIRS values
- Preoperative and postoperative diagnosis
- Length of hospital stay
- Postoperative complications
- Biopsy results
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for appendectomies for acute appendicitis at the emergency unit of our institution
- •Patients older than 15 years of age to 100 years of age
排除标准
- •Appendectomy performed incidentally or for other indications
- •Patients younger than 15 years of age
- •Alcoholism
- •A history of viral hepatitis
- •Gilbert's disease
- •Dubin Johnson syndrome
- •BRIC (benign recurrent intra-hepatic cholestasis) and other documented biliary
- •Hemolytic or liver diseases associated with hyperbilirubinaemia
研究者
研究点 (1)
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