Optimal Positive End-Expiratory Pressure in Robotic-Assisted Thoracic Surgery Without Capnothorax
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Respiratory system compliance
研究概览
简要总结
The aim of this study is to assess the impact on lung mechanics during robotic lung resection when no capnothorax is used.
详细描述
Assess the improvement of oxygenation, ventilation and lung mechanics in patients ventilated with individualized PEEP without capnothorax. PEEP requirement and lung mechanics without capnothorax will be compared with a historical cohort population of robotic surgery with capnothorax.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing uniportal robotic lung resection under no capnothorax
排除标准
- •Refusal to participate
- •Contraindications to recruitment maneuvers
结局指标
主要结局
Respiratory system compliance
时间窗: During intra-operative mechanical ventilation (4 hours)
Respiratory pressures measurement will be combined to obtain respiratory system compliance. Respiratory system compliance = (plateau pressure-PEEP) / respiratory tidal volume (expressed in cmH2O/mL)
Respiratory airway pressures
时间窗: During intra-operative mechanical ventilation (4 hours)
Respiratory airway pressures (peak pressure, plateau pressure and PEEP in cmH2O)
Respiratory rate
时间窗: During intra-operative mechanical ventilation (4 hours)
Respiratory rate (in cycles per minute)
次要结局
- Arterial blood gas parameters: pO2(During intra-operative mechanical ventilation (4 hours))
- Arterial blood gas parameters: pCO2(During intra-operative mechanical ventilation (4 hours))
- Arterial blood gas parameters: pH(During intra-operative mechanical ventilation (4 hours))
- Arterial blood gas parameters: sodium bicarbonate(During intra-operative mechanical ventilation (4 hours))
- Arterial blood gas parameters: base excess(During intra-operative mechanical ventilation (4 hours))