Modulations of gut microbiota and metabolites by dietary intervention with heat-stabilised rice bran in adults of high risk colorectal cancer - a double blinded randomized controlled study

Chinese University of Hong Kong0 个研究点目标入组 40 人开始时间: 2020年11月25日最近更新: 2021年11月29日

试验速览

2021 Results article in https://doi.org/10.3390/nu13020526 (added 23/11/2021)

•1. Chinese aged 50 or above
•2. Categorised as a high risk group for the development of CRC (score 4-7) by the Asian-Pacific Colorectal Screening tool (APCS)
•3. No gastrointestinal symptoms suggestive of colorectal cancer
•4. Negative fecal occult blood test or negative colonoscopy findings for CRC within 1 year
•5. No history of food allergy
•6. No dietary restriction
•7. Not currently taking cholesterol-lowering medications
•8. Not currently taking non-steroidal anti-inflammatory drugs (NSAIDs)
•9. No probiotic and prebiotics use for the past 3 months
•10. No history of gallstones
•11. No Chinese medicine use (except traditional Chinese soup) for the past 3 months
•12. No antibiotic taking for the past 3 months

•1. Having lower gastrointestinal symptoms in the past week
•2. Currently pregnant unless sterilization was done or in menopause or lactating (self-reported by the participants)
•3. Diagnosed to have diabetes mellitus

发起方