Association between early echocardiographic parameters of hemodynamic significance and plasma NT pro-BNP and a composite outcome of death or postnatal morbidities by 36 weeks postmenstrual age in preterm neonates of 25-29 weeks gestation with echocardiographic evidence of patent ductus arteriosus: a prospective cohort study

none0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

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•Neonates born in the unit between 25 to 29 weeks and 6 days will be eligible for inclusion

•1. Antenatally suspected or proven congenital heart disease
•2. Suspected congenital heart disease (other than PDA) on the first screening postnatal
•echocardiography (would be however
•included if proven as normal by a Pediatric
•cardiologist before the echo done on
•3. Major or life threatening congenital
•malformation
•4. Suspected congenital rubella infection based on the maternal positive serology for IgM
•rubella antibodies anytime during the
•current pregnancy
•5. PDA that did not remain open beyond 24 hours of age as well as did not cause a PDA ssociated acute hemodynamic worsening in the first
•24 hours of life
•All consecutively inborn neonates in the gestational age of 25 to 29 6/7 weeks would be
•screened with Portable Ultrasound Machine between 12-24 hours of life for presence of
•patent ductus arteriosus with pure
•or predominant left to right shunt
•across the ductus arteriosus as
•per the unit policy.
•Is the subject

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