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临床试验/NCT06088966
NCT06088966招募中不适用

Evaluation of Hemodynamic and Ventilatory Effects of Negative Pressure Ventilation

Karlsburg Hospital1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2023年8月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
30
试验地点
1
主要终点
Stroke Volume Index in ml/m2

研究概览

简要总结

Investigation of the effects of negative pressure ventilation after cardiac surgery in adults onto performance of the left and right heart and the lungs.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Cross Sectional

入排标准

性别
All
接受健康志愿者

入选标准

  • patients with pulmonary artery catheter after cardiac surgery

排除标准

  • minimally invasive surgery
  • unstable conditions
  • unability to fit cuirass

结局指标

主要结局

Stroke Volume Index in ml/m2

时间窗: 1 hour

次要结局

  • right ventricular ejection fraction in %(1 hour)
  • blood pressure in mm/Hg(1 hour)
  • right ventricular fractional area change in %(1 hour)
  • Vena contract of tricuspid valve in mm(1 hour)
  • Heart rate in beats/min(1 hour)
  • end diastolic volume index in ml/m2(1 hour)
  • Cardiac index in l/min/m2(1 hour)
  • arterial oxygen saturation in %(1 hour)
  • mixed venous oxygen saturation in %(1 hour)
  • tricuspid annular plane systolic excursion in mm(1 hour)

研究者

发起方
Karlsburg Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Prof. Dr. Matthias Heringlake

Clinical Professor and head of the department of anesthesiology and intensive care Prof. Dr. Matthias Heringlake

Karlsburg Hospital

研究点 (1)

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