Initial Clinical and CBCT Outcomes of Enamel Matrix Derivative-Based Regenerative Therapy in Vertical Bone Defects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- Clinical attachment level in mm
研究概览
简要总结
Study of the effectiveness of the application of regenerative therapy with autogenous, platelet-rich plasma in vertical defects Investigation of the effectiveness of the application of regenerative therapy with enamel matrix derivatives in vertical bone defects Study of the effectiveness of the application of guided tissue regeneration in vertical bone defects with Barrier membrane and Barrier membrane and autogenous platelet-rich plasma
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •good oral hygiene
- •written informed consent
- •no systemic diseases
排除标准
- •horizontal bone loss
- •untreated periodontium disease
研究组 & 干预措施
GTR (barrier membrane)
干预措施: Guided Tissue Regeneration (barrier membrane) (Procedure)
GTR(barrier membrane and PRP)
干预措施: Guided Tissue Regeneration(barrier membrane and PRP) (Procedure)
PRP alone
干预措施: PRP( platelet rich plasma) (Procedure)
EMD Alone
干预措施: EMD (Enamel Matrix Derivative) (Procedure)
结局指标
主要结局
Clinical attachment level in mm
时间窗: 6 months
The width of the bone defect in mm
时间窗: 6 months
Probing depth in mm
时间窗: 6 months
Level of Margo Gingivalis in mm
时间窗: 6 months
The distance from the ECJ to the base of the bone defect in mm
时间窗: 6 months
The distance from the ECJ to the apex of the bone defect in mm
时间窗: 6 months
次要结局
未报告次要终点
研究者
Tsvetalina Gerova-Vatsova
Assistant
Medical University of Varna