Alterations of Fronto-Cerebello-Frontal Loops in Attention Deficit Hyperactivity Disorder (ADHD) : A Study Using Magnetic Resonance Imaging (MRI)
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 19
- 试验地点
- 4
- 主要终点
- Fractional anisotropy coefficient if fronto-cerebello-frontal loops.
研究概览
简要总结
The aim of this study is to investigate the integrity of connectivity between the neocortex and the cerebellum in the Attention Deficit Hyperactivity Disorder (ADHD). Fibers integrity will be measured using magnetic Resonance Imaging Techniques.
详细描述
ADHD is a neurodevelopmental trouble characterized by attentional deficits, impulsivity and motor hyperactivity. Morphological neuroimaging studies in ADHD children have revealed cerebellar abnormalities, however data in adults regarding cerebellum alterations are scarce. In this study we will analyse the conectivity of the cerebellum of adults ADHD patients. We will use diffusion tensor imaging (DTI) technique, and morphological data will be compared with the neuropsychological status.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patient with ADHD :
- •Diagnosis of ADHD
- •18 - 35 years old
- •Healthy volunteer :
- •18 - 35 years old
- •no ADHD diagnosed
排除标准
- •Associated neurological or psychiatric pathologies
- •Pregnant woman
- •MRI counter indication
结局指标
主要结局
Fractional anisotropy coefficient if fronto-cerebello-frontal loops.
时间窗: visite 1
次要结局
未报告次要终点