跳至主要内容
临床试验/NCT06896838
NCT06896838招募中不适用

Comparison of Intercostal and Quadriceps Femoris Muscle Oxygenation During Upper Extremity and Lower Extremity Maximal Exercise Tests in Women and Men

Kirsehir Ahi Evran Universitesi1 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2025年6月4日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
28
试验地点
1
主要终点
Maximal symptom limited cycle ergometer test

研究概览

简要总结

The differences in physiological responses due to gender during exercise tests have recently begun to be investigated. The oxygen use of respiratory muscles and lower extremity muscles may differ during upper and lower extremity exercise tests, but there is no study on this subject in the literature. The primary aim of this study was to compare intercostal and quadriceps femoris muscle oxygenation during upper extremity and lower extremity maximal exercise tests in women and men. The secondary aim of the study was to investigate the relationship between intercostal and quadriceps femoris muscle oxygenation and upper extremity and lower extremity exercise capacity, body composition, respiratory muscle strength, and respiratory muscle endurance in women and men.

详细描述

Differences in physiological responses due to gender during exercise tests have recently been investigated. In a study, it was determined that respiratory muscles such as intercostals use more oxygen during exercise tests in women. It was shown that this situation is related to the smaller rib cage, mechanical disadvantage of the diaphragm, narrower airway diameter and greater activation of accessory respiratory muscles in women. The fact that respiratory muscles consume more oxygen in women causes blood flow to the respiratory muscles to be higher. This situation causes a decrease in the amount of oxygen carried to the peripheral muscles, which may cause early fatigue in the peripheral muscles during the exercise test. Muscle oxygen saturation (SmO2) indicates the oxygen uptake and oxygen consumption of the muscle. This can be determined using continuous wave near infrared spectroscopy (NIRS, 630-850 nm) device, which measures changes in the amount of hemoglobin bound to oxygen at the microvascular level. Research on gender-related differences and how SmO2 levels in these muscles change during exercise in women is limited. The aim of the study was to compare intercostal and quadriceps femoris muscle oxygenation during upper extremity and lower extremity maximal exercise tests in women and men.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Aged between 18-35 years,
  • •Physically active (doing moderate intensity physical activity 3 days a week for 150 minutes / week)
  • •Volunteer to participate in the study will be included in the study.

排除标准

  • •Healthy individuals with any diagnosed chronic or systemic disease,
  • •Those who smoke 10 packs x years or more,
  • •Those with pneumonia or any acute infection,
  • •Those with any psychiatric disorder will not be included in the study.

结局指标

主要结局

Maximal symptom limited cycle ergometer test

时间窗: First day

In order to evaluate the exercise capacity of individuals, a symptom-limited increasing workload exercise test will be applied on a bicycle ergometer. In the test, patients will warm up at 0 watts for 3 minutes and then proceed to the loading period of the test. During the loading period, patients will be provided with a 20-watt workload increase every 2 minutes to reach their maximal workload. Patients will be encouraged to continue testing to the maximum level they can sustain during the test. The test will be terminated by the practitioner when patients reach their maximal heart rate or if they wish to terminate the test due to symptoms.

Maximal symptom limited arm ergometer test

时间窗: Second day

Arm ergometer test will be used to evaluate the upper extremity exercise capacity of individuals. The test will be performed in a sitting position with the ergometer height at shoulder level. The arm ergometer test will begin at 0 watts (W) workload and 45-55 rpm at each stage. The workload will be increased by 10 W every two minutes. The highest workload reached during the test will be recorded as watt.

Evaluation of Quadriceps Femoris Muscle Oxygenation

时间窗: First day

Muscle oxygen level and total hemoglobin level of quadriceps femoris will be measured using Moxy® monitor (Moxy, Fortiori Design LLC, Minnesota, USA) before cycle ergometer test, during testing and during post-test recovery.

Evaluation of Intercostals Muscle Oxygenation

时间窗: Second day

Muscle oxygen level and total hemoglobin level of and intercostal muscles will be measured using Moxy® monitor (Moxy, Fortiori Design LLC, Minnesota, USA) before arm ergometer test, during testing and during post-test recovery.

次要结局

  • Evaluation of respiratory muscle strength(Second day)
  • Evaluation of body composition(First day)
  • Evaluation of respiratory muscle endurance(Second day)

研究者

发起方
Kirsehir Ahi Evran Universitesi
申办方类型
Other
责任方
Principal Investigator
主要研究者

Başak KAVALCI KOL

Principle Investigator

Kirsehir Ahi Evran Universitesi

研究点 (1)

Loading locations...

相似试验