NL-OMON35702已完成不适用
Effects of RAS inhibition on insulin sensitivity and IGF-I bioactivity - RAS inhibition, insulin sensitivity and IGF-I bioactivity
Ikazia Ziekenhuis0 个研究点目标入组 40 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- age 18 * 70 years
- •- impaired fasting glucose (IFG): fasting plasma glucose levels between 5,6 * 6,9 mmol/l (100 * 125 mg/dl) and/or impaired glucose tolerance (IGT): plasma glucose levels between 7,8 * 11,0 mmol/l (140 * 199 mg/dl) after 2 hours on the 75-g oral glucose tolerance test
排除标准
- •- use of RAS inhibitors within 6 weeks prior to inclusion
- •- use of oral glucose-lowering drugs or insulin
- •- use of statins
- •- use of betablockers
- •- use of steroids, hormone replacement therapy or other study medication
- •- contraindication for or intolerant to RAS inhibitors
- •- untreated hypothyroidism or hyperthyroidism
- •- negroid race
- •- pregnancy and breastfeeding
- •- severe renal insufficiency (GFR < 30mL/min) and/or known bilateral renal artery stenosis
- •- hyperpotassemia (potassium > 5,0mmol/L)
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